Pynocare is a trusted brand helping Filipinos achieve their melasma-free skin goals. This oral supplement blends science with simplicity, packing a powerful punch with key ingredients like Procyanidin, an antioxidant that battles pigmentation at its root, and Vitamins A, C, and E, the trio of skin-repair champions. Together, they make for one of the best, if not the best solution for melasma that is currently available in the market.

Best Solution for Melasma – The Pynocare Advantage

Unlike topical treatments, Pynocare works from the inside, offering convenience in capsule form. It is clinically-proven to reduce melasma patches and hyperpigmentation in as fast as 8 weeks. It is also the only FDA-approved medication for melasma in the Philippines to date.  Its key ingredients include:

Procyanidin: A potent antioxidant that reduces oxidative stress, one of the factors contributing to pigmentation. Studies suggest it may inhibit melanin production, reducing the size and intensity of dark patches.

Vitamins A, C, and E: Known for their skin-protective properties, these vitamins boost cell regeneration, fight free radicals, and lighten dark spots over time.

Can Pynocare Be Your Go-To Melasma Solution?

Pynocare offers a promising alternative for those seeking holistic melasma management. Its antioxidant-rich formula targets pigmentation while enhancing skin health, making it an appealing choice for many. However, individual results depend on factors like melasma type, severity, and adherence to complementary treatments like sun protection. Let’s take a deeper look at some of the frequently asked questions about melasma and Pynocare.

1. What is Melasma and are there different kinds of it?

Commonly referred to as “pekas” in the Philippines, melasma is a prevalent skin condition characterized by brown to gray-brown patches on the face. It is one of the most common skin concerns in the country, where the tropical climate and frequent sun exposure make Filipinos particularly prone to pigmentation problems.

Melasma forms due to overproduction of melanin, the pigment responsible for skin color. Factors like UV exposure, hormonal shifts (e.g., pregnancy or contraceptive use), and genetic predisposition trigger or exacerbate this condition. Stress and certain medications can also contribute. Melasma manifests in three main types:

1. Epidermal: Limited to the outer skin layer, appearing as dark, defined patches.
2. Dermal: Occurs deeper in the skin, with lighter and blurry patches.
3. Mixed: Combines features of both, making treatment more complex.

2. What are the current solutions for melasma?

Traditional treatments include topical creams containing hydroquinone, retinoids, or azelaic acid, chemical peels, and advanced methods like laser therapy.

While effective for some, these approaches may irritate sensitive skin or yield temporary results, highlighting the need for alternatives like oral supplements. With this, the best solution for melasma will require more than just one approach.

3. What is Pynocare and is it safe to take?

            Pynocare is an over-the-counter medication intended for melasma. It contains 24 mg Procyanidin (as French Maritime Pine Bark Extract), 60 mg Ascorbic Acid (Vitamin C),  6 mg Beta carotene (Vitamin A, as D. Salina Extract), and 15 IU d-Alpha Tocopheryl Acetate (Vitamin E).

This formulation is clinically-proven and tested to help fade melasma in as little as 8 weeks of continuous use. It has undergone rigorous clinical studies including safety studies to ensure it is safe for use. One of the clinical trials was even conducted here in the Philippines with Filipino test subjects. So, when you take Pynocare for your melasma concerns, you are also exposed to the same external conditions (weather, environment, etc.) as to the subjects in the study.

4. How effective is Pynocare?

The study mentioned above along with other studies conducted in Malaysia and Thailand have shown the effectiveness of Pynocare for melasma.

The one conducted here in the Philippines measured effectiveness in terms of changes in pigmentation were measured using a mexameter, melasma area and severity index (MASI), and global evaluation of the patient and the researchers.

1. Mexameter: A mexameter is an instrument used to measure the absorption or reflection of light. Values range from 1 to 1000, with zero representing white and 1000 representing black. In the study, the mexameter values provide an estimate of the melanin and hemoglobin (erythema) content of the skin. This means that patients with higher mexameter readings have essentially darker melasma pigmentation.
2. Melasma Area and Severity Index (MASI): The MASI scores of the patients were calculated based on the area of involvement, darkness of melasma, and homogeneity of pigmentation. Four areas on the face were evaluated: forehead, right malar (right cheek) region, left malar (left cheek) region, and chin, which represented 30%, 30%, 30%, and 10% of the face, respectively.
3. Subjective evaluation of patients and researchers: At the end of the study, both the patients and researchers filled out an evaluation form based on their subjective assessment on the improvement of their melasma. They were asked if they think that their/their patients’ melasma has “no improvement”, “slight improvement”, “moderate improvement”, “obvious improvement”, or “very marked improvement”.

1. Where can I get Pynocare? How much?

            Pynocare is available in all leading drugstores nationwide including Mercury Drug, Watsons, Southstar Drug, Rose Pharmacy, and St. Joseph Drug. It is also available online on Shopee and Lazada via LifePal Pharmacy or via eBotika PH. Make sure to buy your Pynocare only from these trusted distributors to ensure that you are not getting fake ones. Beware especially online where there have been reports of fake websites offering fake Pynocare at a cheaper price.

            The suggested retail price for Pynocare is Php 70.00/capsule or Php 1,400.00/box of 20 capsules. It could be cheaper by a few pesos depending on the store but you should be cautious when it is offered at a significantly lower price.

2. How to identify fake Pynocare?

            There are a number of signs that you need to look out for. Here are some things to know about how to identify fake Pynocare.

1. No print on blister foil: Authentic Pynocare shows the details and its formulation printed on the blister foil. Fake Pynocare does not have any blister prints.
2. Capsule shape: Fake Pynocare capsules appear to be more pointed and longer than the authentic ones that are rounder and have no points.
3. Check the box: Identifying fake Pynocare can also be seen on the packaging. On fake Pynocare boxes, it will show that the product is imported and distributed by Royal Drug, Inc., while the authentic brand is imported and distributed by Metro Drug, Inc. It is also wise to check the spelling of the information, as some words (package vs. package) are misspelled. The fonts are also different, as the fake ones look darker.
4. Blister pack: While the authentic Pynocare has wide blister packs and comes with a divider in the middle, the fake Pynocare does not have this, and its blister pack is also significantly slimmer.

 7. How to take Pynocare?

            Pynocare is taken one capsule twice a day or as recommended by your physician. Despite being relatively safe on its own, it is important to consult your healthcare provider before taking melasma especially if you have other medical conditions or taking other medications that can interact with the components present in Pynocare.

8. What are the side effects of Pynocare?

Very rare side effects can be experienced when taking Pynocare. One of the main side effects is stomach upset, which can be prevented when the medication is taken with meals.

            Studies for Procyanidin, like the one from 2004 where they evaluated 80 mg of procyanidin for 30 days, showed adverse effects including headache, dizziness, diarrhea, and fatigue in a minority of the participants.The study conducted here in the Philippines, none of those adverse effects were reported by the participants. Only one participant developed a metallic taste and subsequently dropped out from the study.

9. How long should I take Pynocare?

            Positive results from taking Pynocare can be seen in as fast as 8 to 12 weeks depending on the severity of melasma. You can take it for a longer period but make sure it is under the discretion and advice of a medical professional. You should also report any side effect experienced especially when it is beyond what is expected.

10. Can I take Pynocare longer than 8 weeks?

            Yes, you can. However, this should be under your doctor’s supervision and advice. One of the challenges of melasma treatment is recurrence where melasma pigmentations come back. Pynocare can be taken as maintenance to avoid this from happening. It can also be taken as a preventive measure for melasma if you are at a high risk of getting one.

11. Can teenagers take Pynocare?

            Pynocare is not recommended for children or teenagers. It is very important to consult your healthcare provider before giving Pynocare to children or teenagers since there is no Pynocare studies conducted yet for this age group.

The Best Solution for Melasma

The best solution for melasma remains to be a holistic approach to managing it. Pynocare represents a complementary approach to melasma treatment, addressing pigmentation from within and promoting overall skin health. While promising, it should be used under professional guidance as part of a broader strategy.

Disclaimer: The information provided in this article is based on scientific literature and aims to offer insights into hyperpigmentation and its treatment options. However, it is intended for informational purposes only and should not be considered a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare professional for personalized advice regarding any medical concerns or conditions.

References
Handog, E. B., Galang, D. A., de Leon-Godinez, M. A., & Chan, G. P. (2009). A randomized, double-blind, placebo-controlled trial of oral procyanidin with vitamins A, C, E for melasma among Filipino women. International Journal of Dermatology, 48(8), 896–901. https://doi.org/10.1111/j.1365-4632.2009.04130.x

Rauf, A., Imran, M., Abu-Izneid, T., Iahtisham-Ul-Haq, N., Patel, S., Pan, X., Naz, S., Silva, A. S., Saeed, F., & Suleria, H. a. R. (2019). Proanthocyanidins: A comprehensive review. Biomedicine & Pharmacotherapy, 116, 108999. https://doi.org/10.1016/j.biopha.2019.108999

PYNOCARE (Procyanidin + Ascorbic Acid + Betacarotene + d-Alpha-Tocopheryl Acetate)

The first and only oral medicine that is clinically proven to reduce Melasma or dark spots formation in just 8 weeks. Unlike creams, lotions, and gels, it has MSCC or Melasma Skin Clear Complexion Complex formulation that deeply penetrates the inner layers of the skin, to help normalize melanin levels, thus minimizing the appearance of dark spots in a short time.

Mega We Care

Mega Lifesciences Limited Inc. or Mega We Care, is actively involved in helping millions of people have access to safe, effective, world-class quality nutritional & herbal supplements, OTC, and ethical products.