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Clinical Studies / FDA Approved

Clinically Tested in the Philippines

“In this 8-week trial period, oral procyanidin + vitamins AC, E proved to be safe and effective among Filipino women with epidermal melasma.”

Excerpt from a randomized, double blind, placebo-controlled trial of oral procyanidin with vitamins A, C, E on melasma among Filipino women.

Evangeline B. Handog, MD, FPDS, FAAD
Ma. Dulce Amor Vivian L. Feliciano, MD, 2009

Clinically Tested in Malaysia

Shahrir MS et al, J of Int. Med Dec 2004

Clinically Tested in Thailand

Dr. Fabrice Perin, Spincontrol, Thailand July 2004

Approved as OTC drug by FDA

Pynocare (Procyanidin + Ascorbic Acid + Betacarotene + d-Alpha-Tocopheryl Acetate) proven effective thus FDA has categorized it as an OTC drug that can treat melisma.

FDA Registration Number: DR-XY29636.

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Product Information

PYNOCARE (Procyanidin + Ascorbic Acid + Betacarotene + d-Alpha-Tocopheryl Acetate) is the first and only oral medicine that is clinically proven to reduce Melasma or dark spots formation in just 8 weeks. Unlike creams, lotions and gels, it has MSCC or Melasma Skin Clear Complexion Complex formulation that deeply penetrates the inner layers of the skin to help normalize melanin levels, thus minimizing the appearance of dark spots in a short time.

Women who tried Pynocare
Available in Drugstores Nationwide


For many years I spent a lot on trying products that didn’t lighten my dark spots. Kaya naman pala.
I had this skin condition that’s called melisma.
I didn’t know what to do. Pati nga self-confidence ko naapektuhan.
Until I discovered Pynocare. At first, I thought ang mahal…But why not? I just had to try it.
After 8 weeks, yung melisma ko aba! Naglighten!
Feeling ko bumata ako!
Sa dami ng natry ko, Pynocare ang nag work! It’s really worth it!

Gaye Piccio

My dark spots came because of hormonal changes during my last pregnancy.
Years after I gave birth, andun pa rin ang dark spots. I found out that I had a skin condition pala, it was melisma. I’m very particular about the products I take so maingat ako sa ginagamit ko for my skin. Buti na lang I found clinically tested product Pynocare! After 8 weeks of taking it, yung melisma ko nag-lighten na. I’m glad I have Pynocare to mother my skin.

Trinidad Naval

One day I suddenly noticed some dark spots on my face. I remember my mom also had the same skin condition. It’s called melisma. So I consulted a derma who prescribed Pynocare and assured me that it’s clinically tested. I took it for 8 weeks, my melasma became lighter. They were barely there! My derma knows best. Now I feel beautiful.

Francesca Sarausa


Have a question in mind?

Frequently Asked Questions

1. Where can I buy PYNOCARE in the Philippines?

PYNOCARE (Procyanidin + Ascorbic Acid + Betacarotene + d-Alpha-Tocopheryl Acetate) is an over-the-counter drug available at Mercury, Watsons, Southstar, Rose, St. Joseph pharmacy, and other leading drugstores nationwide.

3. How many capsules does 1 box have?

Each box has 20 capsules.

2. What is the recommended dosage?

1 capsule twice daily with meals for 8 weeks. Preferably after breakfast and in the afternoon.
Deep Melasma may take up to 12 weeks of 2x daily to see visible results. As maintenance, 1 capsule a day can prevent recurrence of melasma.
*If symptoms persist, consult your doctor.

4. How soon can I expect to see results?

With continuous use of PYNOCARE (Procyanidin + Ascorbic Acid + Betacarotene + d-Alpha-Tocopheryl Acetate), it’s possible to see visible results in at least eight weeks.Results vary from person to person depending on the type of pigmentation.

Available in Drugstores Nationwide

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The First Oral Medicine for Melasma